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Digital Stereotaxic with Manual Fine Drive With 3 or 6 Axes Display
Leica stereotaxic instruments with digital, as opposed to vernier, scales offer greater speed of operation with reduced opportunity for error. This compact instrument features linear position-sensing digital scales and a convenient remote display center.
Simply move the probe to Bregma and touch the zeroing button. Once all displays read zero, move the probe until each of the three axes displays the desired coordinates.
Leica manipulators include a low mounted manual fine drive on the dorsal ventral manipulator to minimize hand-generated vibration of the probe, and avoid overshoot. In addition, this manipulator includes a high torque compression clamp system on the tilt mechanism for the greatest stability.
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Fine Drive
Manual Fine Drive reduces risk of overshoot, and reduces hand-transmitted vibration.
Reduced Risk of Human Error
Touch probe to Bregma, touch zero button for each axis, and move to the target coordinate. No reading vernier scales, writing down numbers, or doing arithmetic.
Testimonials
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Leica PELORIS improving workflow, safety, and productivity
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Publications
The following publications cite the Leica Biosystem’s Digital Stereotaxic instrument for Research Use Only.
- Kyle A.Windisch, C. L. C. (2018). Effects of group II metabotropic glutamate receptor modulation on ethanol- and sucrose-seeking and consumption in the rat. Alcohol, 66, 77–85. Retrieved from www.sciencedirect.com/science/article/pii/S0741832917307942!
- Ahn, S. Y., Chang, Y. S., Kim, Y. E., Sung, S. I., Sung, D. K., & Park, W. S. (2018). Mesenchymal stem cells transplantation attenuates brain injury and enhances bacterial clearance in Escherichia coli meningitis in newborn rats. Pediatric Research, 84(5), 778–785. doi.org/10.1038/s41390-018-0142-5
- Chang, Y. S., Ahn, S. Y., Sung, D. K., Kim, Y. E., Sung, S. I., Joo, S. Y., & Park, W. S. (2018). Developing a newborn rat model of meningitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli. BioRxiv, 384750. doi.org/10.1101/384750
- Im, G. H., Kim, S. M., Lee, D.-G., Lee, W. J., Lee, J. H., & Lee, I. S. (2013). Fe3O4/MnO hybrid nanocrystals as a dual contrast agent for both T1- and T2-weighted liver MRI. Biomaterials, 34(8), 2069–2076. doi.org/10.1016/J.BIOMATERIALS.2012.11.054
- Acharya, M. M., Roa, D. E., Bosch, O., Lan, M. L., & Limoli, C. L. (2011). Stem cell transplantation strategies for the restoration of cognitive dysfunction caused by cranial radiotherapy. Journal of Visualized Experiments : JoVE, (56). doi.org/10.3791/3107
- Seo, T.-B., Kim, B.-K., Ko, I.-G., Kim, D.-H., Shin, M.-S., Kim, C.-J., … Kim, H. (2010). Effect of treadmill exercise on Purkinje cell loss and astrocytic reaction in the cerebellum after traumatic brain injury. Neuroscience Letters, 481(3), 178–182. doi.org/10.1016/J.NEULET.2010.06.087
- Chen, Q., Butler, D., Querbes, W., Pandey, R. K., Ge, P., Maier, M. A., … Sah, D. W. Y. (2010). Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery. Journal of Controlled Release, 144(2), 227–232. doi.org/10.1016/J.JCONREL.2010.02.011
- Querbes, W., Ge, P., Zhang, W., Fan, Y., Costigan, J., Charisse, K., … Sah, D. W. Y. (2009). Direct CNS Delivery of siRNA Mediates Robust Silencing in Oligodendrocytes. Oligonucleotides, 19(1), 23–30. doi.org/10.1089/oli.2008.0165