Navinci is a Swedish biotechnology company specializing in developing innovative solutions for studying proteins, protein-protein interactions, and post-translationally modified proteins in cells and tissues. With a focus and strong legacy in developing in situ proximity ligation assay technology, Navinci has established itself as a center of excellence in the spatial biology field and has a broad portfolio of products that help academic researchers and biopharma study the protein interplay in depth.
The Naveni® BOND RX products offer a comprehensive solution for studying PD1/PD-L1 interactions within the tissue microenvironment. With precise visualization capabilities, researchers can gain deeper insights into the dynamics of immune checkpoint pathways, facilitating the development of targeted immunotherapies for cancer treatment.
Naveni® BOND RX products enable researchers to explore complex protein-protein interactions with high precision and accuracy using their own primary antibodies. By visualizing these interactions within the spatial context of cells and tissues, researchers can unravel intricate signaling networks and uncover novel therapeutic targets for various diseases.
An example is the interactions between CD8 and MHC-I. Understanding these interactions is vital for elucidating the role of cytotoxic T cells in immune surveillance and their involvement in diseases such as cancer and autoimmune disorders.
With Naveni® BOND RX products, researchers can investigate protein function and signaling events within the tissue microenvironment, shedding light on key biological processes and uncovering new avenues for therapeutic intervention. An example is the dynamic interplay between E-Cadherin and Beta-catenin. Providing insights into cell adhesion and signaling pathways is crucial for understanding tissue organization and the progression of various diseases, including carcinoid tumors.
R&D Project lead
Hampus Elofsson leads the effort to fully automate Navinci’s next-generation in situ proximity ligation assays, with the vision that Navinci’s assays should work with minimal effort from the customer and still maintain the same high quality, no matter where in the world the technology is used.
Application Scientist
Doroteya Raykova is an expert in method development and assays for in situ detection of protein-protein interactions and a passionate reader and writer of scientific texts. Her mission is to ensure that the Naveni® technology reaches those whose research can benefit from it, provide technical expertise, and help with setting up and troubleshooting.
Chief Product and Science Officer
Agata Wicher leads in spatial proteomics, overseeing product development and scientific affairs. Her work bridges scientific research with product innovation, aligning with business strategies for market relevance and industry advancement.
For Research Use Only. Not for use in diagnostic procedures.
