Skip to main content
Knowledge-Pathway-Hero-image

Case Base Versus Single Piece IHC Workflows Evaluated in a Large Reference Laboratory

The Leica Biosystems Process and Solutions Optimization team has partnered with a high-volume reference laboratory to evaluate the potential impact of a case based IHC workflow versus an individual slide workflow.

The Leica Biosystems team observed current IHC protocols, staining instrument utilization, and case completion process. This reference laboratory performed 122,733 IHC stains utilizing 2 different staining systems. System 1 included 7 IHC stainers with random access slide capability and System 2 contained 3 stainers with 3, 10-slide racks. Currently, 22 steps, including 2 manual processes are required to complete the IHC staining procedure in System 1. By completing a time and motion study, the Leica Biosystems Process & Solutions Optimization team determined significant LEAN laboratory savings of time, overproduction, and talent.

By evaluating both instrument workfl ows, significant manual sorting times were observed, and data analysis identified the following:

  • Total sorting times for fi lling both instruments averaged 4 minutes, 24 seconds for System 1 and 1 minute, 32 seconds for System 2. Total of 5 minutes, 56 seconds combined per run.

Image
Current-avg-sort-time1
Fig 1(Above) : Current Average Sort Time

 

Time studies further revealed a manual slide rinse and counterstain process specifi c to System 1. By eliminating manual sorting, counterstaining, and slide rinsing with System 2’s case-based approach, appropriate instrumentation utilization can yield substantial improvements in time savings, hand-on time, and touchpoints.

Current hands-on time for System 1:

  • Individual slide staining process totals 89.8 seconds per slide, totaling 3059 hours per year.

Image
Hands-On-Time-Comparison
Fig 2(Above) : Hands On Time Comparison

Proposed hands-on time for System 2:

  • Case base model reduces total hands on time to 28.2 seconds per slide, totaling 961 total hours per year a 69% difference between current and proposed staining processes.
Image
csm_69percent-reduction_in_hands_35a67cb743
그림 3(위): 작업 시간 69% 단축

Projections and Realized Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.


Leica Biosystems 콘텐츠는 Leica Biosystems 웹사이트 이용 약관의 적용을 받으며, 이용 약관은 다음에서 확인할 수 있습니다. 법적고지. 라이카 바이오시스템즈 웨비나, 교육 프레젠테이션 및 관련 자료는 특별 주제 관련 일반 정보를 제공하지만 의료, 규정 또는 법률 상담으로 제공되지 않으며 해석되어서는 안 됩니다. 관점과 의견은 발표자/저자의 개인 관점과 의견이며 라이카 바이오시스템즈, 그 직원 또는 대행사의 관점이나 의견을 나타내거나 반영하지 않습니다. 제3자 자원 또는 콘텐츠에 대한 액세스를 제공하는 콘텐츠에 포함된 모든 링크는 오직 편의를 위해 제공됩니다.

모든 제품 사용에 다양한 제품 및 장치의 제품 정보 가이드, 부속 문서 및 작동 설명서를 참조해야 합니다.

Copyright © 2024 Leica Biosystems division of Leica Microsystems, Inc. and its Leica Biosystems affiliates. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.