Peer-Reviewed Publications Repository - BOND RXm

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Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression

Publication Year: 2022
Country: USA
PMID: PMC8955233
Publication: Viruses. 2022;14(3):535. doi:10.3390/v14030535
Institute: Louisiana Animal Disease Diagnostic Laboratory (LADDL), Louisiana State University, Baton Rouge, LA 61329
Instrument: BOND RXm
Authors: Carossino M, Kenney D, O’Connell AK, et al.
Study Goals: To analyze neuroinvasion and neurodissemination in humans call into question the translational relevance of this model.
Keywords: BOND RXm, translational animal model; comparative pathology; immunohistochemistry; in situ hybridization; viral pathogenesis; transmission electron microscopy; in vivo imaging
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Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model

Publication Year: 2021
Country: France
PMID: PMC8376007
Publication: PLOS Pathogens. 2021;17(8):e1009427. doi:10.1371/journal.ppat.1009427
Institute: Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse

Instrument:

 BOND RXm
Authors: Bessière P, Wasniewski M, Picard-Meyer E, et al.
Study Goals: To investigate whether early type I IFN treatment is beneficial, while late interventions are ineffective, although not associated with signs of enhanced disease.
Keywords: BOND RXm
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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

Publication Year: 2021
Country: USA
PMID: PMC7930198
Publication: Nature Communications. 2021;12(1). doi:10.1038/s41467-021-21615-4
Institute: Fred Hutchinson Cancer Research Center, Seattle, WA

Instrument:

 BOND RXm
Authors: Brady L, Kriner M, Coleman I, et al.
Study Goals: To demonstrate the utility of digital spatial profiling for accurately classifying tumor phenotype, assessing tumor heterogeneity, and identifying aspects of tumor biology involving the immunological composition of metastases.
Keywords: BOND RXm, metastatic prostate cancer, tumor heterogeneity, tumor phenotype, digital spatial profiling (DSP), multiplex
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Immunohistochemical Characterization of a Duodenal Adenocarcinoma with Pulmonary, Hepatic and Parapatellar Metastases in a Common Marmoset (Callithrix jacchus)

Publication Year: 2021
Country: USA
PMID: N/A
Publication: Journal of Comparative Pathology
Institute: Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, Maryland

Instrument:

BOND RXm
Authors: Peterson C, Plunkard J, Johanson A, Izzi J, Gabrielson K.
Study Goals: To investigate proximal duodenal adenocarcinoma with extensive metastatic disease in a common marmoset
Keywords: BOND RXm, common marmoset; duodenal mucinous adenocarcinoma; metastases; pancytokeratin

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