Fully Automated Workflows for High Plex Multi-omic Profiling with GeoMx® Digital Spatial Profiler and BOND RX/ BOND RXm Research Stainer
NanoString’s GeoMx® DSP allows for the characterization of spatial distribution and abundance of proteins and RNA with morphological context. This extends the ability for enhanced translational research in many areas including immunology, oncology, and neuropathology with downstream analysis of analyte abundance by nCounter or Next Generation Sequencing.
Learning Objectives
- Describe four multi-omics analysis areas (RNA and Protein analysis) that a spatial solution can impact
- Identify three ways spatial profiling helps investigators answer research questions (Geometric, segmentation, etc.)
- Explain three workflow improvements that may be achieved by fully automating GeoMx RNA assays on the BOND RX
To enhance both throughput and reproducibility, we recently have developed a fully automated sample processing RNA workflow for use with the BOND RX fully automated research stainer from Leica Biosystems. This workflow on the BOND RX allows a 4-fold increase in sample processing with minimal hands-on time.
Additionally, through NanoString’s partnership with Illumina, automated secondary analysis has been enabled for the NextSeq 1000/2000, thereby further enabling a truly automated end-to-end workflow.
For Research Use Only. Not for Use in Diagnostic Procedures.
About the presenter
Nick Confuorto is a Senior Director Global Field Applications at Nanostring Technologies where he is responsible for leading the development and execution of the strategic plan for the GeoMx Digital Spatial Profiling (DSP) business unit. Prior to joining Nanostring, Nick held several commercial roles across the Life Sciences industry with experience in bringing to market new capabilities in the Imaging, Flow Cytometry, and Mass Spectrometry fields. Nick has a strong passion for introducing cutting edge technologies that can accelerate Translational Research with the ultimate promise of benefiting patient care through precision medicine.
Related Content
El contenido de Leica Biosystems Knowledge Pathway está sujeto a las condiciones de uso del sitio web de Leica Biosystems, disponibles en: Aviso legal.. El contenido, incluidos los webinars o seminarios web, los recursos de formación y los materiales relacionados, está destinado a proporcionar información general sobre temas concretos de interés para los profesionales de la salud y no está destinado a ser, ni debe interpretarse como asesoramiento médico, normativo o jurídico. Los puntos de vista y opiniones expresados en cualquier contenido de terceros reflejan los puntos de vista y opiniones personales de los ponentes/autores y no representan ni reflejan necesariamente los puntos de vista ni opiniones de Leica Biosystems, sus empleados o sus agentes. Cualquier enlace incluido en el contenido que proporcione acceso a recursos o contenido de terceros se proporciona únicamente por comodidad.
Para el uso de cualquier producto, debe consultarse la documentación correspondiente del producto, incluidas las guías de información, los prospectos y los manuales de funcionamiento.
Copyright © 2024 Leica Biosystems division of Leica Microsystems, Inc. and its Leica Biosystems affiliates. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.